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ResearchTrusted Source has found that, alongside psychotherapy, MDMA could be effective in the treatment of other mental health conditions, such as:

• post-traumatic stress disorder (PTSD)
• anxiety in association with a life threatening illness
• social anxiety in autistic adults

MDMA may, therefore, also work to treat additional mental health conditions, including depression. It may provide benefits in people already using psychotherapy as a treatment.

Currently, researchers need more evidence to determine whether MDMA could be a safe and effective treatment for depression.

It is also vital to note that the MDMA that researchers use in clinical settings is free of the potentially harmful additives in the drugs that people purchase illegally.