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Meanwhile,; MDMA is an amphetamine derivative, capable of crossing the blood–brain barrier to the central nervous system, where its major substrates are the vesicular and presynaptic monoamine transporters Elliott and Beveridge, 2005.  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  . . .